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We note that the biotic regulation concept justifies the urgent necessity to conserve undisturbed ecosystems on a planetary scale on the basis of strictly pragmatic reasoning backed by quantitative arguments. Whatever our personal subjective attitude to nature (admiration, love, rejection, indifference, ignorance etc.), the existence of globally important territories occupied by undisturbed ecosystems is an objective and indispensable condition of the personal survival of every human being and his or her direct offspring.